GITR Antibody Panel (EPR20566, CAL8, CAL52) (ab252195)
Overview
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Product name
GITR Antibody Panel (EPR20566, CAL8, CAL52)
See all GITR kits -
Species reactivity
Reacts with: Human -
Product overview
GITR Antibody Panel ab252195 contains multiple trial-sized versions of anti-human antibody clones against GITR, specifically selected for high performance in IHC. This panel contains 3 recombinant rabbit monoclonal antibodies against human GITR. They are provided in trial sizes to allow you to easily evaluate which is the best GITR antibody for your IHC research assay needs.
For guidelines on how to use each antibody within the panel, please consult the individual datasheet for each antibody.
Panel contains:
- Rabbit monoclonal [CAL52] to GITR (20 µL) ab237713
- Rabbit monoclonal [CAL8] to GITR (20 µL) ab237714
- Rabbit monoclonal [EPR20566] to GITR (20 µL) ab223841
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Notes
Explore our range of antibody sample panels designed to provide you with a variety of trial-size antibodies in a convenient and cost-effective format.
Carrier-free formulations of our recombinant antibodies are available and ready to use for multiplex IHC analysis including Imaging Mass CytometryTM. Please refer to the ‘Associated products’ section below.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Storage instructions
Store at -20°C. Please refer to protocols. -
Components 1 kit ab237713 - Anti-GITR antibody [CAL52] 2 x 10µl ab237714 - Anti-GITR antibody [CAL8] 2 x 10µl ab223841 - Anti-GITR antibody [EPR20566] 2 x 10µl -
Research areas
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Function
Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. -
Tissue specificity
Expressed in lymph node, peripheral blood leukocytes and weakly in spleen. -
Sequence similarities
Contains 3 TNFR-Cys repeats. -
Cellular localization
Secreted and Cell membrane. - Information by UniProt
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Alternative names
- Activation inducible TNFR family receptor
- Activation-inducible TNFR family receptor
- AITR
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Database links
- Entrez Gene: 8784 Human
- Omim: 603905 Human
- SwissProt: Q9Y5U5 Human
- Unigene: 212680 Human
Images
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Immunohistochemical analysis of paraffin-embedded human Hodgkin's lymphoma tissue labeling GITR with ab223841 at 1/1000 dilution, followed by Goat Anti-Rabbit IgG H&L (HRP) Ready to use. Cytoplasmic staining in sporadic cells (arrows) in human Hodgkin’s lymphoma (PMID: 25787078; PMID: 23785514). Counter stained with hematoxylin.
Secondary antibody only control: Used PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG H&L (HRP) Ready to use.
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Formalin-fixed, paraffin-embedded human tonsil tissue stained for GITR using ab237714 at 0.5 μg/ml in immunohistochemical analysis.
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Formalin-fixed, paraffin-embedded human tonsil tissue stained for GITR using ab237713 at 0.25 μg/ml in immunohistochemical analysis.
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