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GITR Antibody Panel (EPR20566, CAL8, CAL52) (ab252195)

Price and availability

348 441 ₸

Availability

Order now and get it on Tuesday March 09, 2021

GITR Antibody Panel (EPR20566, CAL8, CAL52) (ab252195)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

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Overview

  • Product name

    GITR Antibody Panel (EPR20566, CAL8, CAL52)
    See all GITR kits
  • Species reactivity

    Reacts with: Human
  • Product overview

    GITR Antibody Panel ab252195 contains multiple trial-sized versions of anti-human antibody clones against GITR, specifically selected for high performance in IHC. This panel contains 3 recombinant rabbit monoclonal antibodies against human GITR. They are provided in trial sizes to allow you to easily evaluate which is the best GITR antibody for your IHC research assay needs.


    For guidelines on how to use each antibody within the panel, please consult the individual datasheet for each antibody.


    Panel contains:


    - Rabbit monoclonal [CAL52] to GITR (20 µL) ab237713


    - Rabbit monoclonal [CAL8] to GITR (20 µL) ab237714


    - Rabbit monoclonal [EPR20566] to GITR (20 µL) ab223841

  • Notes

    Explore our range of antibody sample panels designed to provide you with a variety of trial-size antibodies in a convenient and cost-effective format.

    Carrier-free formulations of our recombinant antibodies are available and ready to use for multiplex IHC analysis including Imaging Mass CytometryTM. Please refer to the ‘Associated products’ section below.

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Properties

  • Storage instructions

    Store at -20°C. Please refer to protocols.
  • Components 1 kit
    ab237713 - Anti-GITR antibody [CAL52] 2 x 10µl
    ab237714 - Anti-GITR antibody [CAL8] 2 x 10µl
    ab223841 - Anti-GITR antibody [EPR20566] 2 x 10µl
  • Research areas

    • Immunology
    • Innate Immunity
    • Cytokines
    • Necrosis Factors
    • Signal Transduction
    • Growth Factors/Hormones
    • TNF
    • Cancer
    • Growth factors
    • TNF
    • Immunology
    • Adaptive Immunity
    • Regulatory T Cells
  • Function

    Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
  • Tissue specificity

    Expressed in lymph node, peripheral blood leukocytes and weakly in spleen.
  • Sequence similarities

    Contains 3 TNFR-Cys repeats.
  • Cellular localization

    Secreted and Cell membrane.
  • Target information above from: UniProt accession Q9Y5U5 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Alternative names

    • Activation inducible TNFR family receptor
    • Activation-inducible TNFR family receptor
    • AITR
    • CD357
    • GITR
    • GITR D
    • GITR-D
    • GITRD
    • Glucocorticoid induced TNFR related protein
    • glucocorticoid-induced tnf receptor ligand
    • glucocorticoid-induced tnf receptors ligand
    • Glucocorticoid-induced TNFR-related protein
    • TNF receptor superfamily activation inducible protein
    • TNFRSF 18
    • TNFRSF18
    • TNR18_HUMAN
    • Tumor necrosis factor receptor superfamily member 18
    • Tumor necrosis factor receptor superfamily member 18 precursor
    see all
  • Database links

    • Entrez Gene: 8784 Human
    • Omim: 603905 Human
    • SwissProt: Q9Y5U5 Human
    • Unigene: 212680 Human

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GITR antibody [EPR20566]
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GITR antibody [EPR20566]

      Immunohistochemical analysis of paraffin-embedded human Hodgkin's lymphoma tissue labeling GITR with ab223841 at 1/1000 dilution, followed by Goat Anti-Rabbit IgG H&L (HRP) Ready to use. Cytoplasmic staining in sporadic cells (arrows) in human Hodgkin’s lymphoma (PMID: 25787078; PMID: 23785514). Counter stained with hematoxylin.

      Secondary antibody only control: Used PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG H&L (HRP) Ready to use.

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GITR antibody [CAL8]
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GITR antibody [CAL8]

      Formalin-fixed, paraffin-embedded human tonsil tissue stained for GITR using ab237714 at 0.5 μg/ml in immunohistochemical analysis.

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GITR antibody [CAL52]
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GITR antibody [CAL52]

      Formalin-fixed, paraffin-embedded human tonsil tissue stained for GITR using ab237713 at 0.25 μg/ml in immunohistochemical analysis.

    • GITR Antibody Panel (EPR20566, CAL8, CAL52) (ab252195)
      GITR Antibody Panel (EPR20566, CAL8, CAL52) (ab252195)

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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