Recombinant Mouse PD1 protein (Fc Chimera) (Biotin) (ab216222)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 90% SDS-PAGE
- Tags: Avi tag C-Terminus
- Suitable for: SDS-PAGE
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Product name
Recombinant Mouse PD1 protein (Fc Chimera) (Biotin)
See all PD1 proteins and peptides -
Purity
> 90 % SDS-PAGE. -
Expression system
HEK 293 cells -
Accession
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Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Mouse -
Sequence
LEVPNG PWRSLTFYPA WLTVSEGANA TFTCSLSNWS EDLMLNWNRL SPSNQTEKQA AFCNGLSQPV QDARFQIIQL PNRHDFHMNI LDTRRNDSGI YLCGAISLHP KAKIEESPGA ELVVTERILE TSTRYPSPSP KPEGRFQ -
Amino acids
25 to 167 -
Tags
Avi tag C-Terminus -
Additional sequence information
Corresponding to the extracellular domain, fused at the C-terminus to the Fc portion of mouse IgG2a (NM_008798). This protein was biotinylated using AviTagTM technology.
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Conjugation
Biotin
Preparation and Storage
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Alternative names
- CD279
- CD279 antigen
- hPD 1
see all -
Function
Possible cell death inducer, in association with other factors. -
Involvement in disease
Genetic variation in PDCD1 is associated with susceptibility to systemic lupus erythematosus type 2 (SLEB2) [MIM:605218]. Systemic lupus erythematosus is a chronic, inflammatory and often febrile multisystemic disorder of connective tissue. It affects principally the skin, joints, kidneys and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system. -
Sequence similarities
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
Developmental stage
Induced at programmed cell death. -
Cellular localization
Membrane. - Information by UniProt
Images
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SDS-PAGE - Recombinant Mouse PD1 protein (Fc Chimera) (Biotin) (ab216222)
4-20% SDS-PAGE analysis of ab216222 (4 µg, lane 1).
Note: this protein runs at an apparent higher molecular weight due to glycosylation.
