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Neuroscience Neurology process Neurodegenerative disease Alzheimer's disease Proteases

FITC Anti-Urokinase antibody (ab28223)

Key features and details

  • FITC Rabbit polyclonal to Urokinase
  • Reacts with: Human
  • Conjugation: FITC. Ex: 493nm, Em: 528nm
  • Isotype: IgG

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Overview

  • Product name

    FITC Anti-Urokinase antibody
    See all Urokinase primary antibodies
  • Description

    FITC Rabbit polyclonal to Urokinase
  • Host species

    Rabbit
  • Conjugation

    FITC. Ex: 493nm, Em: 528nm
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Full length protein: uPA purified from human urine.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C.
  • Storage buffer

    pH: 6.60
    Constituents: 0.82% Sodium phosphate, 0.0292% EDTA, 0.58% Sodium chloride
  • Concentration information loading...
  • Purification notes

  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Neuroscience
    • Neurology process
    • Neurodegenerative disease
    • Alzheimer's disease
    • Proteases
    • Cardiovascular
    • Blood
    • Fibrinolysis / Thrombolysis
    • Cancer
    • Cancer Metabolism
    • Response to hypoxia
    • Metabolism
    • Pathways and Processes
    • Metabolism processes
    • Hypoxia
    • Metabolism
    • Types of disease
    • Neurodegenerative disease
    • Metabolism
    • Types of disease
    • Cancer

Associated products

  • Isotype control

    • FITC-Rabbit IgG - Isotype Control (ab37406)
  • Recombinant Protein

    • Recombinant mouse Urokinase protein (ab92641)

Target

  • Function

    Specifically cleave the zymogen plasminogen to form the active enzyme plasmin.
  • Tissue specificity

    Expressed in the prostate gland and prostate cancers.
  • Sequence similarities

    Belongs to the peptidase S1 family.
    Contains 1 EGF-like domain.
    Contains 1 kringle domain.
    Contains 1 peptidase S1 domain.
  • Post-translational
    modifications

    Phosphorylation of Ser-158 and Ser-323 abolishes proadhesive ability but does not interfere with receptor binding.
  • Cellular localization

    Secreted.
  • Target information above from: UniProt accession P00749 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 5328 Human
    • Omim: 191840 Human
    • SwissProt: P00749 Human
    • Unigene: 77274 Human
    • Alternative names

      • ATF antibody
      • ATF uPA antibody
      • BDPLT5 antibody
      • Plasminogen activator antibody
      • Plasminogen activator urinary antibody
      • Plasminogen activator urokinase antibody
      • PLAU antibody
      • QPD antibody
      • u PA antibody
      • U plasminogen activator antibody
      • u-PA antibody
      • U-plasminogen activator antibody
      • uPA antibody
      • URK antibody
      • UROK_HUMAN antibody
      • Urokinase plasminogen activator antibody
      • Urokinase type plasminogen activator antibody
      • Urokinase type plasminogen activator precursor antibody
      • Urokinase-type plasminogen activator chain B antibody
      see all

    Protocols

    • Western blot protocols

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab28223? Please let us know so that we can cite the reference in this datasheet.

    ab28223 has not yet been referenced specifically in any publications.

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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