Anti-Urokinase antibody (ab24122)
Key features and details
- Goat polyclonal to Urokinase
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Urokinase antibody
See all Urokinase primary antibodies -
Description
Goat polyclonal to Urokinase -
Host species
Goat -
Specificity
The antibody is highly specific for urokinase, no crossreactions were found with other serine proteases (tissue plasminogen activator, plasmin, trypsin, chymotrypsin, elastase, thrombin). -
Species reactivity
Reacts with: Human -
Immunogen
Extensively purified HMW-tcuPA and LMW-scuPA (mixture 50/50), isolated from urine (Human).
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General notes
ab24122 binds to human HMW-scuPA (54 kDa), HMW-tsuPA (52 kDa) and LMW-scuPA (33 kDa) with high apparent affinity (Kd= 0.1 nM) completely inhibiting the ability of urokinase to activate plasminogen. Urokinase reaction with synthetic substrate S2444 is also inhibited. Human whole plasma or plasma proteins do not interfere with its binding to urokinase.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.5
Constituent: PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Primary antibody notes
ab24122 binds to human HMW-scuPA (54 kDa), HMW-tsuPA (52 kDa) and LMW-scuPA (33 kDa) with high apparent affinity (Kd= 0.1 nM) completely inhibiting the ability of urokinase to activate plasminogen. Urokinase reaction with synthetic substrate S2444 is also inhibited. Human whole plasma or plasma proteins do not interfere with its binding to urokinase. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
