PTEN is a protein implicated in several disease, including certain cancers and neurological diseases. PTEN is expressed ubiquitously throughout the body and acts as a phosphatase to dephosphorylate phosphatidylinositol (3,4,5)-trisphosphate. This is important in the inhibition of the Akt signalling pathway, which plays an important role in regulating cellular behaviours such as cell growth, survival, and migration.

This product is a recombinant monoclonal antibody, which offers several advantages including:

• - High batch-to-batch consistency and reproducibility
• - Improved sensitivity and specificity
• - Long-term security of supply
• - Animal-free production

Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result of this work we are pleased to now offer this antibody in purified format. We are in the process of updating our datasheets. The purified format is designated 'PUR' on our product labels. If you have any questions regarding this update, please contact our Scientific Support team.