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Anti-MDM2 (phospho S186) antibody [2G2] (ab22710)

Key features and details

  • Mouse monoclonal [2G2] to MDM2 (phospho S186)
  • Reacts with: Human
  • Isotype: IgG1

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Overview

  • Product name

    Anti-MDM2 (phospho S186) antibody [2G2]
    See all MDM2 primary antibodies
  • Description

    Mouse monoclonal [2G2] to MDM2 (phospho S186)
  • Host species

    Mouse
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide: QRKRHKSpDSIS, corresponding to amino acids 180-190 of Human MDM2.

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • Positive control

    • Breast carcinoma.
  • General notes


    Phosphorylation at serine 166 and 186 is necessary for MDM2's translocation into the nucleus, thereby facilitating interaction with p53.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    Constituent: PBS
  • Concentration information loading...
  • Purity

    Protein A/G purified
  • Primary antibody notes

    Phosphorylation at serine 166 and 186 is necessary for MDM2's translocation into the nucleus, thereby facilitating interaction with p53.
  • Clonality

    Monoclonal
  • Clone number

    2G2
  • Myeloma

    Sp2
  • Isotype

    IgG1
  • Research areas

    • Cell Biology
    • Cell Cycle
    • Cell Cycle Inhibitors
    • p53
    • Epigenetics and Nuclear Signaling
    • Transcription
    • Other factors
    • Cancer
    • Cell cycle
    • Cell cycle inhibitors
    • p53 pathway
    • Cancer
    • Oncoproteins/suppressors
    • Oncoproteins
    • Cell survival & death
    • Epigenetics and Nuclear Signaling
    • Ubiquitin & Ubiquitin Like Modifiers
    • E3 Ubiquitin Ligases

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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