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Immunology Adaptive Immunity T Cells Non-CD

Anti-LY75/DEC-205 antibody [AP-MAB0873] (ab80945)

Key features and details

  • Rat monoclonal [AP-MAB0873] to LY75/DEC-205
  • Reacts with: Mouse
  • Isotype: IgG2

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Overview

  • Product name

    Anti-LY75/DEC-205 antibody [AP-MAB0873]
    See all LY75/DEC-205 primary antibodies
  • Description

    Rat monoclonal [AP-MAB0873] to LY75/DEC-205
  • Host species

    Rat
  • Species reactivity

    Reacts with: Mouse
  • Immunogen

    Tissue, cells or virus corresponding to Mouse LY75/DEC-205.

  • General notes

    Previously labelled as LY75. 

Properties

  • Form

    Lyophilized
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer

    Constituent: PBS
  • Concentration information loading...
  • Purity

    Protein A purified
  • Purification notes

    Endotoxin Level
  • Clonality

    Monoclonal
  • Clone number

    AP-MAB0873
  • Isotype

    IgG2
  • Research areas

    • Immunology
    • Adaptive Immunity
    • B Cells
    • Non-CD
    • Tags & Cell Markers
    • Cell Type Markers
    • Tumor Associated

Associated products

  • Compatible Secondaries

    • Goat Anti-Rat IgG H&L (Alexa Fluor® 488) (ab150157)
    • Goat Anti-Rat IgG H&L (HRP) (ab205720)

Target

  • Function

    Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment (By similarity). Causes reduced proliferation of B-lymphocytes.
  • Tissue specificity

    Expressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells.
  • Sequence similarities

    Contains 10 C-type lectin domains.
    Contains 1 fibronectin type-II domain.
    Contains 1 ricin B-type lectin domain.
  • Post-translational
    modifications

    N-glycosylated.
  • Cellular localization

    Membrane.
  • Target information above from: UniProt accession O60449 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 17076 Mouse
    • SwissProt: Q60767 Mouse
    • Unigene: 2074 Mouse
    • Alternative names

      • C-type lectin domain family 13 member B antibody
      • CD 205 antibody
      • CD205 antibody
      • CD205 antigen antibody
      • CLEC 13B antibody
      • CLEC13B antibody
      • DEC 205 antibody
      • DEC-205 antibody
      • DEC205 antibody
      • gp200 antibody
      • gp200 MR6 antibody
      • gp200-MR6 antibody
      • LY 75 antibody
      • Ly-75 antibody
      • LY75 antibody
      • LY75_HUMAN antibody
      • Lymphocyte antigen 75 antibody
      • Renal Cell Carcinoma (gp200) antibody
      see all

    Protocols

    • Western blot protocols
    • Flow cytometry protocols

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab80945? Please let us know so that we can cite the reference in this datasheet.

    ab80945 has not yet been referenced specifically in any publications.

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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