Anti-GPCR GPR15 antibody (ab8104)
Key features and details
- Rabbit polyclonal to GPCR GPR15
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-GPCR GPR15 antibody
See all GPCR GPR15 primary antibodies -
Description
Rabbit polyclonal to GPCR GPR15 -
Host species
Rabbit -
Tested Applications & Species
See all applications and species dataApplication Species WB Human
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Immunogen
Peptide corresponding to amino acids 13 to 28 of human GPR15 (1). The sequence differs from those ofAfrican green monkey and pig-tailed macaque BOB byone amino acid (2)
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General notes
Human immunodeficiency virus (HIV) and related viruses require co-receptors to infect target cells. Some G protein coupled receptors including CCR5, CXCR4, CCR3,CCR2b and CCR8 in the chemokine receptor family, and four new human molecules GPR15, STRL33, GPR1 and V28 were recently identified as HIV coreceptors. The genes encoding human and monkey GPR15/BOB (for G protein-coupled receptor 15 and brother of Bonzo, respectively) were recently cloned. This novel G protein-coupled receptor serves as coreceptor for simian immunodeficiency virus (SIV), and for strains of HIV-2 and M-tropic HIV-1. The ligand for GPR15 has not been identified yet.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide -
Concentration information loading... -
Purity
Immunogen affinity purified -
Primary antibody notes
Human immunodeficiency virus (HIV) and related viruses require co-receptors to infect target cells. Some G protein coupled receptors including CCR5, CXCR4, CCR3,CCR2b and CCR8 in the chemokine receptor family, and four new human molecules GPR15, STRL33, GPR1 and V28 were recently identified as HIV coreceptors. The genes encoding human and monkey GPR15/BOB (for G protein-coupled receptor 15 and brother of Bonzo, respectively) were recently cloned. This novel G protein-coupled receptor serves as coreceptor for simian immunodeficiency virus (SIV), and for strains of HIV-2 and M-tropic HIV-1. The ligand for GPR15 has not been identified yet. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Images
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Western blot - Anti-GPCR GPR15 antibody (ab8104)All lanes : Anti-GPCR GPR15 antibody (ab8104)
Lane 1 : Human heart lysate in absence of specific peptide
Lane 2 : Human heart lysate in presence of specific peptide
Lane 3 : Human heart lysate in presence of unrelated peptide
Observed band size: 50 kDa why is the actual band size different from the predicted?
Western blot analysis of GPR15 in human heart lysate with anti- GPR15 (NT) in the absence (lane 1) or presence of specific peptide (lane 2) or non related peptide (lane 3). -
Western blot - Anti-GPCR GPR15 antibody (ab8104)Lane 1 : Anti-GPCR GPR15 antibody (ab8104) at 0.5 µg/ml
Lane 2 : Anti-GPCR GPR15 antibody (ab8104) at 1 µg/ml
All lanes : Human spleen lysate
Observed band size: 50 kDa why is the actual band size different from the predicted?
