YM298198 hydrochloride, mGlu1 antagonist (ab120015)
Key features and details
- Potent, selective mGlu1 antagonist
- CAS Number: 748758-45-4
- Purity: > 99%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
YM298198 hydrochloride, mGlu1 antagonist -
Description
Potent, selective mGlu1 antagonist -
Biological description
Potent, selective, water-soluble, non-competitive mGlu1 antagonist (IC50 = 16 nM) Selective over mGlu2,3,4,5,6, and 7 and ionotropic receptors (IC50 > 10 μM). Orally active analgesic in vivo.
Also available in simple stock solutions (ab146667) - add 1 ml of water to get an exact, ready-to-use concentration. -
Purity
> 99% -
CAS Number
748758-45-4 -
Chemical structure
Properties
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Chemical name
6-Amino-N-cyclohexyl-N,3-dimethylthiazolo[3,2-a]benzimidazole-2-carboxamide hydrochloride -
Molecular weight
378.92 -
Molecular formula
C18H22N4OS.HCl -
PubChem identifier
45073464 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Cl.CN(C1CCCCC1)C(=O)c3sc4nc2ccc(N)cc2n4c3C -
Source
Synthetic
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Research areas
