CPCCOEt, mGlu1 antagonist (ab120060)
Key features and details
- Selective, non-competitive mGlu1 antagonist
- CAS Number: 179067-99-3
- Purity: > 98%
- Soluble in DMSO to 100 mM and in ethanol to 5 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
CPCCOEt, mGlu1 antagonist -
Description
Selective, non-competitive mGlu1 antagonist -
Biological description
Potent, selective non-competitive mGlu1 metabotropic glutamate receptor antagonist (IC50 = 6.5 μM at hmGluR1 with no activity at hmGluR2, -4a, -5a, -7b, and -8a up to 100 μM).
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Purity
> 98% -
CAS Number
179067-99-3 -
Chemical structure
Properties
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Chemical name
(E)-Ethyl 1,1a,7,7a-tetrahydro-7-(hydroxyimino)cyclopropa[b]chromene-1a-carboxylate -
Molecular weight
247.25 -
Molecular formula
C13H13NO4 -
PubChem identifier
6278000 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 5 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C(OCC)C13CC3C(=NO)/c2ccccc2O1 -
Source
Synthetic
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Research areas
