TGR5 Receptor Agonist, TGR5 G-protein coupled receptor agonist (ab142091)
Key features and details
- Potent, selective TGR5 G-protein coupled receptor agonist
- CAS Number: 1197300-24-5
- Purity: > 99%
- Soluble in ethanol to 100 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
TGR5 Receptor Agonist, TGR5 G-protein coupled receptor agonist -
Description
Potent, selective TGR5 G-protein coupled receptor agonist -
Biological description
Potent, selective TGR5 G-protein coupled receptor agonist (pEC50 = 6.8). Increases glucagon-like peptide-1 (GLP-1) secretion from primary intestinal cells. Cell-permeable. Active in vivo.
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Purity
> 99% -
CAS Number
1197300-24-5 -
Chemical structure
Properties
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Chemical name
3-(2-Chlorophenyl)-N-(4-chlorophenyl)-N,5-dimethyl-4-isoxazolecarboxamide -
Molecular weight
361.23 -
Molecular formula
C18H14Cl2N2O2 -
PubChem identifier
44605616 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 100 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=C(C(=NO1)C2=CC=CC=C2Cl)C(=O)N(C)C3=CC=C(C=C3)Cl -
Source
Synthetic
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Research areas