Recombinant pig IL-17A protein (ab209272)
Key features and details
- Expression system: Yeast
- Purity: > 95% SDS-PAGE
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE
-
Product name
Recombinant pig IL-17A protein
See all IL-17A proteins and peptides -
Biological activity
The biological activity of ab209272 is determined by the secretion of IL-6 and IL-8 by CΔ2(-) cells after stimulation with IL-17A. Swine IL-6 and IL-8 were produced in a dose response and measured by ELISA or Luminex-based assay. Bioactivity is typically detected at 0.3 ng/mL steadily increasing through 100 ng/mL.
-
Purity
> 95 % SDS-PAGE.
ab209272 was purified by Ion-exchange chromatography. -
Expression system
Yeast -
Accession
-
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
-
Species
Pig -
Sequence
GIMIPQSPGCPKTEDKNFPQHVRVNLNILNRSTPARRPSDYSKRSTSPWT LQRNEDPERYPSVIWEAKCSHSGCINAEGKEDHHMNSVPIQQEILVLRRE PRHCPNSFRLEKVMVTVGCTCVTPIVRHIS -
Predicted molecular weight
15 kDa -
Amino acids
24 to 153 -
Additional sequence information
This product is the mature full length protein from aa 24 to 153. The signal peptide is not included.
-
Preparation and Storage
-
Alternative names
- CTLA 8
- CTLA-8
- CTLA8
see all -
Function
Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of the intracellular adhesion molecule-1 (ICAM-1) in fibroblasts. -
Tissue specificity
Restricted to activated memory T-cells. -
Sequence similarities
Belongs to the IL-17 family. -
Post-translational
modificationsFound both in glycosylated and nonglycosylated forms. -
Cellular localization
Secreted. - Information by UniProt
Images
-
SDS-PAGE - Recombinant pig IL-17A protein (ab209272)
SDS PAGE image of ab202972
