Recombinant human IL-17A protein (Animal Free) (ab217422)
Key features and details
- Expression system: Escherichia coli
- Purity: > 98% SDS-PAGE
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE, HPLC
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Product name
Recombinant human IL-17A protein (Animal Free)
See all IL-17A proteins and peptides -
Biological activity
Measured by its ability to induce IL-6 production by NHDF cells using a concentration range of 0.5-1.5 ng/mL.
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Purity
> 98 % SDS-PAGE.
> 98% by HPLC analysis. -
Expression system
Escherichia coli -
Accession
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Protein length
Full length protein -
Animal free
Yes -
Nature
Recombinant -
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Species
Human -
Sequence
MIVKAGITIPRNPGCPNSEDKNFPRTVMVNLNIHNRNTNTNPKRSSDYYN RSTSPWNLHRNEDPERYPSVIWEAKCRHLGCINADGNVDYHMNSVPIQQE ILVLRREPPHCPNSFRLEKILVSVGCTCVTPIVHHVA -
Predicted molecular weight
31 kDa -
Amino acids
20 to 155 -
Additional sequence information
Disulfide-linked homodimer of two 137 amino acid polypeptide chains.
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Preparation and Storage
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Alternative names
- CTLA 8
- CTLA-8
- CTLA8
see all -
Function
Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of the intracellular adhesion molecule-1 (ICAM-1) in fibroblasts. -
Tissue specificity
Restricted to activated memory T-cells. -
Sequence similarities
Belongs to the IL-17 family. -
Post-translational
modificationsFound both in glycosylated and nonglycosylated forms. -
Cellular localization
Secreted. - Information by UniProt
