Antibodies, Proteins, Kits and Reagents for Life Science

Recombinant human IL-17A protein (Active) (ab256041)

Key features and details

Expression system: Escherichia coli
Purity: > 95% SDS-PAGE
Endotoxin level:
Active: Yes
Suitable for: SDS-PAGE, Functional Studies

Alternative names
- CTLA 8
- CTLA-8
- CTLA8
- cytotoxic T lymphocyte associated antigen 8
- Cytotoxic T lymphocyte associated protein 8
- Cytotoxic T lymphocyte associated serine esterase 8
- Cytotoxic T-lymphocyte-associated antigen 8
- IL 17
- IL 17A
- IL-17
- IL-17A
- IL17
- IL17_HUMAN
- Il17a
- Interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8)
- interleukin 17A
- Interleukin-17A
- interleukin17
- Interleukin17A
- OTTHUMP00000016597
- OTTMUSP00000046003
see all
Function

Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of the intracellular adhesion molecule-1 (ICAM-1) in fibroblasts.
Tissue specificity

Restricted to activated memory T-cells.
Sequence similarities

Belongs to the IL-17 family.
Post-translational
modifications

Found both in glycosylated and nonglycosylated forms.
Cellular localization

Secreted.
Target information above from: UniProt accession Q16552 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

SDS-PAGE - Recombinant human IL-17A protein (ab256041)

SDS-PAGE analysis of ab256041 (1μg) under non-reducing (Lane 1) and reducing (Lane 2) conditions. ab256041 is a homodimer with predicted to have a MW of 31.3 kDa.

4-20% Tris-Glycine gel. Coomassie Blue staining.
Functional Studies - Recombinant human IL-17A protein (ab256041)

Functional analysis of ab256041.

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