Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant human CT-1 protein (ab134868)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Active: Yes
  • Suitable for: Functional Studies, SDS-PAGE

Description

  • Product name

    Recombinant human CT-1 protein
    See all CT-1 proteins and peptides

  • Biological activity

    Measured in a cell proliferation assay using TF-1 Human erythroleukemic cells. The ED50 for this effect is typically 0.25 – 0.85 ng/ml.

  • Purity

    > 95 % SDS-PAGE.
    ab134868 was constructed as a fusion protein and was highly purified using affinity matrix from E. coli. After specific proteinase cleavage, native CT-1 protein was collected and suspended in PBS buffer.

  • Endotoxin level

  • Expression system

    Escherichia coli

  • Accession

    Q16619

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      SRREGSLEDPQTDSSVSLLPHLEAKIRQTHSLAHLLTKYAEQLLQEYVQL QGDPFGLPSFSPPRLPVAGLSAPAPSHAGLPVHERLRLDAAALAALPPLL DAVCRRQAELNPRAPRLLRRLEDAARQARALGAAVEALLAALGAANRGPR AEPPAATASAASATGVFPAKVLGLRVCGLYREWLSRTEGDLGQLLPGGSA

    • Predicted molecular weight

      21 kDa

    • Amino acids

      2 to 201

    • Specifications

    Our Abpromise guarantee covers the use of ab134868 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      Functional Studies

      SDS-PAGE

    • Form

      Liquid

    • Additional notes

      Previously labelled as Cardiotrophin 1. 

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      Constituent: 99% PBS

      This product is an active protein and may elicit a biological response in vivo, handle with caution.

    General Info

    • Alternative names

      • Cardiophin 1
      • Cardiophin1
      • Cardiotrophin I
      • Cardiotrophin-1
      • Cardiotrophin1
      • CardiotrophinI
      • CT 1
      • CT-1
      • CT1
      • CTF 1
      • Ctf1
      • CTF1_HUMAN
      see all

    • Function

      Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor.

    • Tissue specificity

      Highly expressed in heart, skeletal muscle, prostate and ovary. Lower levels in lung, kidney, pancreas, thymus, testis and small intestine. Little or no expression in brain, placenta, liver, spleen, colon or peripheral blood leukocytes.

    • Sequence similarities

      Belongs to the IL-6 superfamily.

    • Cellular localization

      Secreted.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab134868? Please let us know so that we can cite the reference in this datasheet.

ab134868 has not yet been referenced specifically in any publications.

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Constituent: 99% PBS

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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