Recombinant mouse CT-1 protein (ab201409)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE, HPLC
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Product name
Recombinant mouse CT-1 protein
See all CT-1 proteins and peptides -
Biological activity
Fully biologically active when compared to standard.
The ED50 as determined by a cell proliferation assay using Human TF1 cells is less than 0.5 ng/ml, corresponding to a specific activity of > 2.0 × 106 IU/mg.
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Purity
> 95 % SDS-PAGE.
>95% by HPLC analysis. -
Expression system
Escherichia coli -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Mouse -
Sequence
MSQREGSLEDHQTDSSISFLPHLEAKIRQTHNLARLLTKYAEQLLEEYVQ QQGEPFGLPGFSPPRLPLAGLSGPAPSHAGLPVSERLRQDAAALSVLPAL LDAVRRRQAELNPRAPRLLRSLEDAARQVRALGAAVETVLAALGAAARGP GPEPVTVATLFTANSTAGIFSAKVLGFHVCGLYGEWVSRTEGDLGQLVPG GVA -
Predicted molecular weight
22 kDa -
Amino acids
1 to 203 -
Additional sequence information
Single non-glycosylated polypeptide chain.
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Preparation and Storage
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Alternative names
- Cardiophin 1
- Cardiophin1
- Cardiotrophin I
see all -
Function
Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor. -
Tissue specificity
Highly expressed in heart, skeletal muscle, prostate and ovary. Lower levels in lung, kidney, pancreas, thymus, testis and small intestine. Little or no expression in brain, placenta, liver, spleen, colon or peripheral blood leukocytes. -
Sequence similarities
Belongs to the IL-6 superfamily. -
Cellular localization
Secreted. - Information by UniProt
