LH 846, CK1delta inhibitor (ab146427)
Key features and details
- Potent, selective CK1δ inhibitor
- CAS Number: 639052-78-1
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
LH 846, CK1delta inhibitor -
Description
Potent, selective CK1δ inhibitor -
Biological description
Potent, selective CK1δ inhibitor (IC50 values are 0.29, 1.3 and 2.5 μM for CK1δ, ε and α, respectively). Induces period lengthening of the circadian rhythm in U2OS cells. -
Purity
> 98% -
CAS Number
639052-78-1 -
Chemical structure
Properties
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Chemical name
N-(5-Chloro-6-methyl-1,3-benzothiazol-2-yl)-2-phenylacetamide -
Molecular weight
316.80 -
Molecular formula
C16H13ClN2OS -
PubChem identifier
851474 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=CC2=C(C=C1Cl)N=C(S2)NC(=O)CC3=CC=CC=C3 -
Source
Synthetic
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Research areas
