Cortistatin-14, Endogenous neuropeptide (ab142506)
Key features and details
- Endogenous neuropeptide that binds all SS receptor subtypes
- CAS Number: 186901-48-4
- Purity: > 95%
- Soluble in water
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Cortistatin-14, Endogenous neuropeptide -
Description
Endogenous neuropeptide that binds all SS receptor subtypes -
Biological description
Endogenous neuropeptide, expressed in the cortex and hippocampus. Structural and functional similarities to somatostatin-14. Binds all somatostatin receptors (IC50 values are 5 (sst1), 0.09 (sst2), 0.3 (sst3), 0.2 (sst4) and 0.3 (sst5) nM respectively). Neuronal depressant and sleep-modulating properties in vivo. Important mediator of immunity and inflammation. -
Purity
> 95% -
CAS Number
186901-48-4 -
Chemical structure
Properties
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Molecular weight
1721.02 -
Molecular formula
C81H113N19O19S2 -
Sequence
PCKNFFWKTFSSCK (Modifications: Disulfide bonds: 2-13) -
PubChem identifier
16133803 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)CC5=CC=CC=C5)CC(=O)N)CCCCN)NC(=O)C6CCCN6)C(=O)NC(CCCCN)C(=O)O)CO)CO)CC7=CC=CC=C7)O -
Source
Synthetic
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Research areas
