Dehydrocostus lactone, Cell proliferation inhibitor (ab142418)
Key features and details
- Cell proliferation inhibitor, induces cell cycle arrest and apoptosis
- CAS Number: 477-43-0
- Purity: > 98%
- Soluble in DMSO to 75 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Dehydrocostus lactone, Cell proliferation inhibitor -
Description
Cell proliferation inhibitor, induces cell cycle arrest and apoptosis -
Biological description
Cell proliferation inhibitor, induces cell cycle arrest and apoptosis. Inhibits NO synthase and TNF-α in LPS-activated macrophages. Cytotoxic T lymphocyte inhibitor in vitro (IC50 = 10 μM). Guaianolide. Immunomodulator and antitumor agent. Active in vivo and in vitro. -
Purity
> 98% -
CAS Number
477-43-0 -
Chemical structure
Properties
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Chemical name
(3aS,6aR,9aR,9bS)-3,6,9-Trimethylidene-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[4,5-b]furan-2-one -
Molecular weight
230.30 -
Molecular formula
C15H18O2 -
PubChem identifier
73174 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 75 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C=C1CCC2C(C3C1CCC3=C)OC(=O)C2=C -
Source
Synthetic
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Research areas
