GR 127935 hydrochloride, 5-HT1B/1D receptor antagonist (ab120523)
Key features and details
- Potent, selective 5-HT1B/1D receptor antagonist
- CAS Number: 148642-42-6
- Purity: > 97%
- Soluble in water to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
GR 127935 hydrochloride, 5-HT1B/1D receptor antagonist -
Description
Potent, selective 5-HT1B/1D receptor antagonist -
Biological description
Potent and selective 5-HT1B/1D receptor antagonist (pKi = 8.5 for both 5-HT1D in rat and 5-HT1D in guinea pig). 100-fold selectivity over 5-HT1A, 5-HT1E, and 5-HT2C. Displays centrally mediated effects upon systemic administration.
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Purity
> 97% -
CAS Number
148642-42-6 -
Chemical structure
Properties
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Chemical name
N-[4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-1,1'-biphenyl-4-carboxamide hydrochloride -
Molecular weight
534.06 -
Molecular formula
C29H31N5O3.HCl -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
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Research areas