BRD-7389, p90 ribosomal S6 kinase RSK inhibitor (ab146161)
Key features and details
- p90 ribosomal S6 kinase RSK inhibitor
- CAS Number: 376382-11-5
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
BRD-7389, p90 ribosomal S6 kinase RSK inhibitor -
Description
p90 ribosomal S6 kinase RSK inhibitor -
Biological description
p90 ribosomal S6 kinase RSK inhibitor (IC50 values are 1.2, 1.5 and 2.4 μM for RSK3, RSK1 and RSK2 respectively). Upregulates insulin expression in pancreatic α-cells. Shows reprogramming effects in terminally differentiated cells. -
CAS Number
376382-11-5 -
Chemical structure
Properties
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Chemical name
1-[(2-Phenylethyl)amino]-3H-naphtho[1,2,3-de]quinoline-2,7-dione -
Molecular weight
366.41 -
Molecular formula
C24H18N2O2 -
PubChem identifier
24870634 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC=C(C=C1)CCNC2=C3C4C(=NC2=O)C=CC=C4C(=O)C5=CC=CC=C53 -
Source
Synthetic
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Research areas
