Bafilomycin B1, macrolide antibiotic (ab143365)
Key features and details
- Macrolide antibiotic. Potent, selective vacuolar-type H+-ATPase inhibitor.
- CAS Number: 88899-56-3
- Purity: > 97%
- Soluble in DMSO to 5 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Bafilomycin B1, macrolide antibiotic -
Description
Macrolide antibiotic. Potent, selective vacuolar-type H+-ATPase inhibitor. -
Biological description
Macrolide antibiotic. Potent and selective vacuolar-type H+-ATPase inhibitor. Orally active. -
Purity
> 97% -
CAS Number
88899-56-3 -
Chemical structure
Properties
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Chemical name
[(2R,4R,5S,6R)-2-Hydroxy-2-[(2S,3R,4S)-3-hydroxy-4-[(2R,3S,6Z,9S,10S,11R,12E,14E)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-6-oxo-1-oxacyclohexadeca-4,6,12,14-tetraen-2-yl]pentan-2-yl]-5-methyl-6-propan-2-yloxan-4-yl] (E)-4-[(2-hydroxy-5-oxocyclopenten-1-yl)amino]-4-oxobut-2-enoate -
Molecular weight
815.99 -
Molecular formula
C44H65NO13 -
PubChem identifier
71312233 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 5 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1CC(=CC=CC(C(OC(=O)C(=CC(=CC(C1O)C)C)OC)C(C)C(C(C)C2(CC(C(C(O2)C(C)C)C)OC(=O)C=CC(=O)NC3=C(CCC3=O)O)O)O)OC)C -
Source
Synthetic
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Research areas
