Ivermectin, Positive allosteric modulator of alpha7 nicotinic acetylcholine receptors (ab141813)
Key features and details
- Positive allosteric modulator of α7 nicotinic acetylcholine receptors
- CAS Number: 70288-86-7
- Purity: > 96%
- Soluble in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Ivermectin, Positive allosteric modulator of alpha7 nicotinic acetylcholine receptors -
Description
Positive allosteric modulator of α7 nicotinic acetylcholine receptors -
Biological description
Positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptor. Allosteric effector of P2X4 receptors. Antihelmintic. Modulates glutamate- and GABA-activated chloride channels. Potentiates glycine-gated currents at low concentrations (30 nM). -
Purity
> 96% -
CAS Number
70288-86-7 -
Chemical structure
Properties
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Chemical name
22,23-Dihydroavermectin B1a -
Molecular weight
875.09 -
Molecular formula
C48H74O14 -
PubChem identifier
6440492 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCC(C)C1C(CCC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C -
Source
Synthetic
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Research areas
