Anti-Angiotensin I antibody (ab8051)
Key features and details
- Rabbit polyclonal to Angiotensin I
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Angiotensin I antibody
See all Angiotensin I primary antibodies -
Description
Rabbit polyclonal to Angiotensin I -
Host species
Rabbit -
Specificity
Specificity of the antisera is confirmed by its ability to bind and precipitate labeled angiotensin I and to be adsorbed by angiotensin. Native angiotensin competes with such binding, while human whole plasma or plasma proteins do not. The antiserum also reacts with angiotensin II (Reactivity in competitive ELISA was shown : 80% to Angiotensin II; 100% to Angiotensin I) -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Dog
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Immunogen
Synthetic peptide:
DRVYIHPFHL
conjugated to BSA by a CDI linker, corresponding to N terminal amino acids 34-43 of Human Angiotensin I. -
General notes
The enzyme renin cleaves angiotensinogen to produce an inactive prohormone, angiotensin I; the latter is transformed to the active molecule angiotensin II by another enzyme, angiotensin-converting enzyme
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.5 -
Concentration information loading... -
Purity
Ion Exchange Chromatography -
Purification notes
Pooled antisera are passed over DEAE-cellulose to produce IgG-enriched fraction, which is further subjected to absorption with immobilized human albumin and immmunoglobuline fractions in order to remove non-specific antibodies. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas