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Neuroscience Cell Type Marker Glia marker Astrocyte marker

Anti-ALDH1L1 antibody - Astrocyte Marker (ab87117)

Price and availability

328 339 ₸

Availability

Order now and get it on Thursday February 25, 2021

Anti-ALDH1L1 antibody - Astrocyte Marker (ab87117)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Rabbit polyclonal to ALDH1L1 - Astrocyte Marker
  • Suitable for: WB
  • Reacts with: Mouse, Rat
  • Isotype: IgG

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Overview

  • Product name

    Anti-ALDH1L1 antibody - Astrocyte Marker
    See all ALDH1L1 primary antibodies
  • Description

    Rabbit polyclonal to ALDH1L1 - Astrocyte Marker
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat
    Predicted to work with: Orangutan
  • Immunogen

    Synthetic peptide within Mouse ALDH1L1 aa 300-400 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Database link: Q8R0Y6
    (Peptide available as ab103935)

  • General notes

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituent: PBS

    Batches of this product that have a concentration
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Neuroscience
    • Cell Type Marker
    • Glia marker
    • Astrocyte marker
    • Cell Biology
    • Apoptosis
    • Intracellular
    • Caspases etc
    • Caspases
    • Signal Transduction
    • Metabolism
    • Energy Metabolism
    • Cancer
    • Cell cycle
    • Cell cycle inhibitors
    • p53 pathway
    • Cancer
    • Oncoproteins/suppressors
    • Tumor suppressors
    • Other
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Energy transfer pathways
    • Energy Metabolism
    • Metabolism
    • Types of disease
    • Cancer

Associated products

  • Compatible Secondaries

    • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
    • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
  • Isotype control

    • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)

Applications

Our Abpromise guarantee covers the use of ab87117 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 100 kDa (predicted molecular weight: 99 kDa).

Target

  • Tissue specificity

    Highly expressed in liver, pancreas and kidney.
  • Sequence similarities

    In the N-terminal section; belongs to the GART family.
    In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
    Contains 1 acyl carrier domain.
  • Cellular localization

    Cytoplasm.
  • Target information above from: UniProt accession O75891 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 107747 Mouse
    • Entrez Gene: 64392 Rat
    • SwissProt: Q8R0Y6 Mouse
    • SwissProt: Q5RFM9 Orangutan
    • SwissProt: P28037 Rat
    • Unigene: 30035 Mouse
    • Unigene: 2328 Rat
    • Alternative names

      • 10 formyltetrahydrofolate dehydrogenase antibody
      • 10 FTHFDH antibody
      • 10-formyltetrahydrofolate dehydrogenase antibody
      • 10-FTHFDH antibody
      • AL1L1_HUMAN antibody
      • Aldehyde dehydrogenase 1 family member L1 antibody
      • Aldehyde dehydrogenase family 1 member L1 antibody
      • aldh1l1 antibody
      • Cytosolic 10-formyltetrahydrofolate dehydrogenase antibody
      • DKFZp781N0997 antibody
      • EC 1.5.1.6 antibody
      • FDH antibody
      • formyltetrahydrofolate dehydrogenase antibody
      • FTHFD antibody
      • OTTHUMP00000155221 antibody
      • OTTHUMP00000214696 antibody
      • OTTHUMP00000214700 antibody
      • OTTHUMP00000222724 antibody
      see all

    Images

    • Western blot - Anti-ALDH1L1 antibody - Astrocyte Marker (ab87117)
      Western blot - Anti-ALDH1L1 antibody - Astrocyte Marker (ab87117)
      All lanes : Anti-ALDH1L1 antibody - Astrocyte Marker (ab87117) at 1 µg/ml

      Lane 1 : Liver (Mouse) Tissue Lysate
      Lane 2 : Brain (Mouse) Tissue Lysate
      Lane 3 : Brain (Rat) Tissue Lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

      Developed using the ECL technique.

      Performed under reducing conditions.

      Predicted band size: 99 kDa
      Observed band size: 100 kDa
      why is the actual band size different from the predicted?


      Exposure time: 4 minutes

    Protocols

    • Immunocytochemistry & immunofluorescence protocols
    • Western blot protocols

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
    • SDS
  • References (32)

    Publishing research using ab87117? Please let us know so that we can cite the reference in this datasheet.

    ab87117 has been referenced in 32 publications.

    • Yang H  et al. Region-specific astrogliosis: differential vessel formation contributes to different patterns of astrogliosis in the cortex and striatum. Mol Brain 13:103 (2020). PubMed: 32698847
    • Adams KL  et al. Endothelin-1 signaling maintains glial progenitor proliferation in the postnatal subventricular zone. Nat Commun 11:2138 (2020). PubMed: 32358570
    • Yi YY  et al. Preventive Effects of Neuroprotective Agents in a Neonatal Rat of Photothrombotic Stroke Model. Int J Mol Sci 21:N/A (2020). PubMed: 32456353
    • VanRyzin JW  et al. Microglial Phagocytosis of Newborn Cells Is Induced by Endocannabinoids and Sculpts Sex Differences in Juvenile Rat Social Play. Neuron 102:435-449.e6 (2019). PubMed: 30827729
    • Jay TR  et al. TREM2 is required for microglial instruction of astrocytic synaptic engulfment in neurodevelopment. Glia 67:1873-1892 (2019). PubMed: 31265185
    View all Publications for this product

    Images

    • Western blot - Anti-ALDH1L1 antibody - Astrocyte Marker (ab87117)
      Western blot - Anti-ALDH1L1 antibody - Astrocyte Marker (ab87117)
      All lanes : Anti-ALDH1L1 antibody - Astrocyte Marker (ab87117) at 1 µg/ml

      Lane 1 : Liver (Mouse) Tissue Lysate
      Lane 2 : Brain (Mouse) Tissue Lysate
      Lane 3 : Brain (Rat) Tissue Lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

      Developed using the ECL technique.

      Performed under reducing conditions.

      Predicted band size: 99 kDa
      Observed band size: 100 kDa
      why is the actual band size different from the predicted?


      Exposure time: 4 minutes

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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