Zamifenacin fumarate, M3 receptor antagonist (ab141511)
Key features and details
- Selective M3 receptor antagonist
- CAS Number: 127308-98-9
- Purity: > 99%
- Soluble in DMSO to 100 mM and in ethanol to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Zamifenacin fumarate, M3 receptor antagonist -
Description
Selective M3 receptor antagonist -
Biological description
Selective M3 receptor antagonist (pKi values are 8.52 (M3), 7.93 (M2), 7.90 (M1) and 7.78 (M4) respectively). Inhibits gastrointestinal motility in vivo without causing cardiovascular effects.
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Purity
> 99% -
CAS Number
127308-98-9 -
Chemical structure
Properties
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Chemical name
(3R)-1-[2-(1,3-Benzodioxol-5-yl)ethyl]-3-(diphenylmethoxy)piperidine fumarate -
Molecular weight
531.60 -
Molecular formula
C27H29NO3.C4H4O4 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C(O)/C=C/C(=O)O.c1cc(cc2OCOc12)CCN5CCC[C@@H](OC(c3ccccc3)c4ccccc4)C5 -
Source
Synthetic
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Research areas