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Biochemicals

Okadaic acid ammonium salt, PP1 and PP2A inhibitor (ab141830)

Key features and details

  • Potent, selective PP1 and PP2A inhibitor
  • CAS Number: 155716-06-6
  • Purity: > 98%
  • Soluble in DMSO and in ethanol
  • Form / State: Solid
  • Source: Halichondria okadai

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Overview

  • Product name

    Okadaic acid ammonium salt, PP1 and PP2A inhibitor
  • Description

    Potent, selective PP1 and PP2A inhibitor
  • Biological description

    Potent, selective PP1 and PP2A inhibitor (IC50 values are 3 and 0.2-1 nM for PP1 and PP2A, respectively). Also available okadaic acid (ab120375) and okadaic acid sodium salt (ab141831). Shows tumor-promoting effects in vivo. Centrally active.
  • Purity

    > 98%
  • CAS Number

    155716-06-6
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    9,10-Deepithio-9,10-didehydroacanthifolicin ammonium salt
  • Molecular weight

    822.04
  • Molecular formula

    C44H68O13.NH3
  • PubChem identifier

    16219809
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO and in ethanol
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Toxic, refer to SDS for further information.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1CCC2(CCCCO2)OC1C(C)CC(C3C(=C)C(C4C(O3)CCC5(O4)CCC(O5)C=CC(C)C6CC(=CC7(O6)C(CCC(O7)CC(C)(C(=O)[O-])O)O)C)O)O.[NH4+]
  • Source

    Halichondria okadai

  • Research areas

    • Biochemicals
    • Chemical Type
    • Biochemicals

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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