YM-01 (YM-1), allosteric Hsp70 modulator (ab146423)
Key features and details
- Allosteric Hsp70 modulator. Potent anti-tau agent.
- CAS Number: 409086-68-6
- Purity: > 98%
- Soluble in water to 5 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
YM-01 (YM-1), allosteric Hsp70 modulator -
Description
Allosteric Hsp70 modulator. Potent anti-tau agent. -
Alternative names
- YM-1
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Biological description
Allosteric Hsp70 modulator. Potent anti-tau agent. MKT-077 analog. Promotes triage functions of Hsp70. Rapidly and potently reduces tau levels ex vivo. Shows antitumor effects in vivo. -
Purity
> 98% -
CAS Number
409086-68-6 -
Chemical structure
Properties
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Chemical name
2-((Z)-((E)-3-Ethyl-5-(3-methylbenzo[d]thiazol-2(3H)-ylidene)-4-oxothiazolidin-2-ylidene)methyl)-1-methylpyridin-1-ium chloride -
Molecular weight
417.97 -
Molecular formula
C20H20ClN3OS2 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 5 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
[Cl-].C[n+]4ccccc4\C=C3/S/C(=C2/Sc1ccccc1N2C)C(=O)N3CC -
Source
Synthetic
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Research areas