Rose Bengal, Glutamate uptake inhibitor (ab145644)
Key features and details
- Potent glutamate uptake inhibitor. Photosensitizing dye.
- CAS Number: 632-69-9
- Soluble in water to 75 mM and in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Rose Bengal, Glutamate uptake inhibitor -
Description
Potent glutamate uptake inhibitor. Photosensitizing dye. -
Biological description
Potent glutamate uptake inhibitor (Ki = 19 nM, glutamate uptake into isolated synaptic vesicles). Photosensitizing dye. Fluorescein derivative. Cell-permeable. Induces photothrombotic stroke in vivo.
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CAS Number
632-69-9 -
Chemical structure
Properties
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Excitation
549nm -
Emission
570nm -
Chemical name
Disodium 2,3,4,5-tetrachloro-6-(2,4,5,7-tetraiodo-6-oxido-3-oxo-3H-xanthen-9-yl)benzoate -
Molecular weight
1017.64 -
Molecular formula
C20H2Cl4I4Na2O5 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 75 mM and in DMSO to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C(O[Na])c4c(Cl)c(Cl)c(Cl)c(Cl)c4C=2c3cc(I)c(O[Na])c(I)c3OC=1C=2C=C(I)C(=O)C=1I -
Source
Synthetic
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Research areas