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VU0155069, PLD1 inhibitor (ab145225)

Key features and details

  • Potent and selective PLD1 inhibitor
  • CAS Number: 1130067-06-9
  • Purity: > 98%
  • Soluble in DMSO to 50 mM or ethanol to 50 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    VU0155069, PLD1 inhibitor
  • Description

    Potent and selective PLD1 inhibitor
  • Biological description

    Potent and selective PLD1 inhibitor (IC50 values are 46 and 933 nM for PLD1 and PLD2 respectively). Inhibits migration in cancer cell lines.
  • Purity

    > 98%
  • CAS Number

    1130067-06-9
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    N-[(2S)-1-[4-(5-Chloro-2-oxo-3H-benzimidazol-1-yl)-piperidin-1-yl]-propan-2-yl]naphthalene-2-carboxamide
  • Molecular weight

    463.00
  • Molecular formula

    C26H27ClN4O2
  • PubChem identifier

    25105713
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 50 mM or ethanol to 50 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

  • Research areas

    • Cardiovascular
    • Lipids / Lipoproteins
    • Lipid Metabolism
    • Lipases
    • Signal Transduction
    • Signaling Pathway
    • Lipid Signaling
    • Other
    • Signal Transduction
    • Signaling Pathway
    • G Protein Signaling
    • Small G Proteins
    • Other
    • Signal Transduction
    • Protein Trafficking
    • Vesicle Transport
    • Regulation
    • Signal Transduction
    • Metabolism
    • Lipid metabolism
    • Biochemicals
    • Product Range
    • New
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Phospholipase & Lipase
    • Inhibitors
    • Biochemicals
    • Pharmacology
    • Signaling
    • Lipid signaling
    • Phospholipase & Lipase
    • Inhibitors
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Lipid and lipoprotein metabolism
    • Lipases

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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