TAPI-0 (TNF alpha processing inhibitor-0), Matrix metalloprotease (MMP) and TACE inhibitor (ab141497)
Key features and details
- TNF-α processing, matrix metalloprotease and TACE inhibitor
- CAS Number: 143457-40-3
- Purity: > 95%
- Soluble in DMSO to 10 mM and in acetic acid to 10 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
TAPI-0 (TNF alpha processing inhibitor-0), Matrix metalloprotease (MMP) and TACE inhibitor -
Description
TNF-α processing, matrix metalloprotease and TACE inhibitor -
Alternative names
- TNFa processing inhibitor0
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Biological description
Inhibits TNF-α processing. Also a general matrix metalloprotease and TACE inhibitor.
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Purity
> 95% -
CAS Number
143457-40-3 -
Chemical structure
Properties
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Chemical name
N-[(2S)-1-[[(2S)-1-Amino-1-oxopropan-2-yl]amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]-N'-hydroxy-2-(2-methylpropyl)butanediamide -
Molecular weight
456.55 -
Molecular formula
C24H32N4O5 -
PubChem identifier
3035404 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 10 mM and in acetic acid to 10 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(C)CC(CC(=O)NO)C(=O)NC(CC1=CC2=CC=CC=C2C=C1)C(=O)NC(C)C(=O)N -
Source
Synthetic
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Research areas
