Sulindac sulfide, COX-1 and 2 inhibitor (ab120650)
Key features and details
- Active metabolite of Sulindac. COX-1 and 2 inhibitor.
- CAS Number: 32004-67-4
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Sulindac sulfide, COX-1 and 2 inhibitor -
Description
Active metabolite of Sulindac. COX-1 and 2 inhibitor. -
Biological description
Cell-permeable, active metabolite of Sulindac. Inhibits Ras-induced malignant transformation and Ras/Raf-dependent transactivation. COX-1 and 2 inhibitor (Ki values are 1.02 and 10.43 μM, respectively). Additionally, inhibits γ-secretase. Apoptosis inducer.
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Purity
> 98% -
CAS Number
32004-67-4 -
Chemical structure
