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Epigenetics and Nuclear Signaling DNA methylation DNMTs

SAM e (S-(5-Adenosyl)-L-methionine disulfate tosylate), Methyl donor (ab142221)

Price and availability

107 212 ₸

Availability

Order now and get it on Friday February 26, 2021

Key features and details

  • Methyl donor and cofactor for enzyme-catalyzed methylations
  • CAS Number: 97540-22-2
  • Purity: > 95%
  • Soluble in water to 100 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    SAM e (S-(5-Adenosyl)-L-methionine disulfate tosylate), Methyl donor
  • Description

    Methyl donor and cofactor for enzyme-catalyzed methylations
  • Biological description

    Methyl donor and cofactor for enzyme-catalyzed methylations, such as catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT).

  • Purity

    > 95%
  • CAS Number

    97540-22-2
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    [(3S)-3-Amino-3-carboxypropyl]-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3, 4-dihydroxyoxolan-2-yl]methyl]methylsulfanium disulfate tosylate
  • Molecular weight

    766.78
  • Molecular formula

    C15H22N6O5S.C7H8O3S.2H2SO4
  • PubChem identifier

    163657
  • Storage instructions

    Shipped at 4°C. Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1=CC=C(C=C1)S(=O)(=O)[O-].C[S+](CCC(C(=O)O)N)CC1C(C(C(O1)N2C=NC3=C2N=CN=C3N)O)O.OS(=O)(=O)[O-].[O-]S(=O)(=O)[O-]
  • Source

    Synthetic

  • Research areas

    • Epigenetics and Nuclear Signaling
    • DNA methylation
    • DNMTs
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Signaling
    • Epigenetics
    • DNA Methyltransferases (DNMTs)
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Transferase
    • DNA Methyltransferase (DNMT)
    • Biochemicals
    • Research Area
    • Cancer
    • Epigenetics
    • DNA Methyltransferases (DNMTs)
    • Biochemicals
    • Research Area
    • Epigenetics
    • DNA Methyltransferases (DNMTs)

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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