RuBi-4AP, Caged K+ channel blocker (ab120410)
Key features and details
- Caged K+ channel blocker, uncaged by visible light
- CAS Number:
- Soluble in water
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
RuBi-4AP, Caged K+ channel blocker -
Description
Caged K+ channel blocker, uncaged by visible light -
Biological description
Water soluble caged 4-aminopyridine (4-AP) based on ruthenium photochemistry. Excited by visible wavelengths and has two-photon uncaging capabilities under physiological conditions. Releases voltage-dependent K+ channel blocker 4-aminopyridine (ab120122) when uncaged.
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General notes
RuBi-4AP is light sensitive and it is recommended that the compound is protected from light.
Sold under license from Columbia University; Patent Pending -
Chemical structure
Properties
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Chemical name
Bis(2,2'-bipyridine-N,N')bis(4-aminopyridine-N1) ruthenium(2+) dichloride complex -
Molecular weight
672.58 -
Molecular formula
C30H28Cl2N8Ru -
Storage instructions
Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions. -
Solubility overview
Soluble in water -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
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Research areas
