TCS OX2 29, Orexin-2 receptor antagonist (ab141316)
Key features and details
- Potent, selective orexin-2 receptor antagonist
- CAS Number: 372523-75-6
- Purity: > 98%
- Soluble in water to 100 mM and in DMSO to 10mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
TCS OX2 29, Orexin-2 receptor antagonist -
Description
Potent, selective orexin-2 receptor antagonist -
Biological description
Potent, selective orexin-2 receptor antagonist (IC50 = 40 nM). Neurological and insomnia agent. Active in vitro and in vivo.
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Purity
> 98% -
CAS Number
372523-75-6 -
Chemical structure
Properties
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Chemical name
(2S)-1-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-3,3-dimethyl-2-[(4-pyridinylmethyl)amino]-1-butanone dihydrochloride -
Molecular weight
470.44 -
Molecular formula
C23H31N3O3.2HCl -
PubChem identifier
53302033 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM and in DMSO to 10mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Cl.Cl.CC(C)(C)[C@H](NCc1ccncc1)C(=O)N2Cc3cc(OC)c(cc3CC2)OC -
Source
Synthetic
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Research areas
