LY2874455, FGF/FGFR inhibitor (ab216313)
Key features and details
- Potent FGF/FGFR inhibitor
- CAS Number: 1254473-64-7
- Purity: > 98%
DMSO (>4 mg/ml)
- Form / State: Solid
- Source: HPLC
Overview
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Product name
LY2874455, FGF/FGFR inhibitor -
Description
Potent FGF/FGFR inhibitor -
Alternative names
- LY-2874455
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Biological description
Potent FGF/FGFR inhibitor. Inhibits in vitro autophosphorylation of FGFR-1, FGFR-2, FGFR-3, and FGFR-4 with similar inhibition potency for all four FGFRs (IC50 in vitro and in vivo selectivity on inhibition of FGF- over VEGF-mediated target signaling in mice.
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Purity
> 98% -
CAS Number
1254473-64-7 -
Chemical structure
Properties
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Chemical name
(R,E)-2-(4-(2-(5-(1-(3,5-dichloropyridin-4-yl)ethoxy)-1H-indazol-3-yl)vinyl)-1H-pyrazol-1-yl)ethanol
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Molecular weight
444.31 -
Molecular formula
C21H19Cl2N5O2 -
PubChem identifier
46944259 -
Storage instructions
Shipped at 4°C. Store at -20°C. Store In the Dark. Store under desiccating conditions. -
Solubility overview
DMSO (>4 mg/ml)
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SMILES
Clc1cncc(Cl)c1[C@@H](C)Oc3cc4c(/C=C/c2cn(CCO)nc2)nnc4cc3 -
Source
HPLC
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Research areas
