Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Rat IL-2 protein (His tag) (ab215022)

Key features and details

  • Expression system: Escherichia coli
  • Purity: >= 95% SDS-PAGE
  • Endotoxin level:
  • Tags: His tag C-Terminus
  • Suitable for: SDS-PAGE

Description

  • Product name

    Recombinant Rat IL-2 protein (His tag)
    See all IL-2 proteins and peptides

  • Purity

    >= 95 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    Escherichia coli

  • Accession

    P17108

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Rat

    • Sequence

      APTSSPAKETQQHLEQLLLDLQVLLRGIDNYKNLKLPMMLTFKFYLPKQA TELKHLQCLENELGALQRVLDLTQSKSFHLEDAGNFISNIRVTVVKLKGS ENKFECQFDDEPATVVEFLRRWIAICQSIISTMTQ

    • Predicted molecular weight

      16 kDa

    • Amino acids

      21 to 155

    • Tags

      His tag C-Terminus

    • Additional sequence information

      This product is the mature full length protein from aa 21 to 155. The signal peptide is not included (NP_446288.1).

    • Specifications

    Our Abpromise guarantee covers the use of ab215022 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

      pH: 7.40
      Constituent: 100% PBS

      Lyophilised from 0.2µm filtered solution.

    • Reconstitution
      Reconstitute in sterile H2O at not less than 100 µg/mL, which can then be further diluted in other aqueous solutions.

    General Info

    • Alternative names

      • Aldesleukin
      • IL 2
      • IL-2
      • IL2
      • IL2_HUMAN
      • Interleukin 2
      • Interleukin-2
      • interleukin2
      • Involved in regulation of T cell clonal expansion
      • Lymphokine
      • OTTHUMP00000164090
      • POIL2
      • T Cell Growth Factor
      • T-cell growth factor
      • TCGF
      see all

    • Function

      Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.

    • Involvement in disease

      Note=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17.

    • Sequence similarities

      Belongs to the IL-2 family.

    • Cellular localization

      Secreted.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab215022? Please let us know so that we can cite the reference in this datasheet.

ab215022 has not yet been referenced specifically in any publications.

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituent: 100% PBS

    Lyophilised from 0.2µm filtered solution.

  • Reconstitution
    Reconstitute in sterile H2O at not less than 100 µg/mL, which can then be further diluted in other aqueous solutions.

Images

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