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Cancer Tumor immunology Cytokines Interleukins

Recombinant Chicken IL-2 protein (ab87392)

Key features and details

  • Expression system: Yeast
  • Purity: > 95% SDS-PAGE
  • Suitable for: SDS-PAGE

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Description

  • Product name

    Recombinant Chicken IL-2 protein
    See all IL-2 proteins and peptides
  • Purity

    > 95 % SDS-PAGE.
    ab87392 is purified by Ion-exchange chromatography.
  • Expression system

    Yeast
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Chicken
    • Sequence

      ASLSSAKRKP LQTLIKDLEI LENIKNKIHL ELYTPTETQE CTQQTLQCYL GEVVTLKKET EDDTEIKEEF VTAIQNIEKN LKSLTGLNHT GSECKICEAN NKKKFPDFLH ELTNFVRYLQ K

Preparation and Storage

  • Alternative names

    • Aldesleukin
    • IL 2
    • IL-2
    • IL2
    • IL2_HUMAN
    • Interleukin 2
    • Interleukin-2
    • interleukin2
    • Involved in regulation of T cell clonal expansion
    • Lymphokine
    • OTTHUMP00000164090
    • POIL2
    • T Cell Growth Factor
    • T-cell growth factor
    • TCGF
    see all
  • Function

    Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.
  • Involvement in disease

    Note=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17.
  • Sequence similarities

    Belongs to the IL-2 family.
  • Cellular localization

    Secreted.
  • Target information above from: UniProt accession P60568 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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