Recombinant mouse IL-2 protein (Active) (ab238291)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Endotoxin level:
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE
Preparation and Storage
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Alternative names
- Aldesleukin
- IL 2
- IL-2
see all -
Function
Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. -
Involvement in disease
Note=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17. -
Sequence similarities
Belongs to the IL-2 family. -
Cellular localization
Secreted. - Information by UniProt
Images
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Functional Studies - Recombinant mouse IL-2 protein (Active) (ab238291)
Induced proliferation of CTLL-2 cells (≤5 ng/mL; ≥ 2.0 x 10^5 units/mg).
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SDS-PAGE - Recombinant mouse IL-2 protein (Active) (ab238291)Recombinant mouse IL2 protein (Active) (ab238291) used at 1 µg run under reducing conditions in a 4-20% Tris-Glycine gel, stained with Coomassie Blue.
