Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant mouse TWEAKR/FN14 protein (ab157284)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Active: Yes
  • Suitable for: Functional Studies, SDS-PAGE

Description

  • Product name

    Recombinant mouse TWEAKR/FN14 protein
    See all TWEAKR/FN14 proteins and peptides

  • Biological activity

    Binds Human and mouse TWEAK.
    Inhibits TWEAK-mediated killing of Kym-1 target cells.

  • Purity

    > 95 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    HEK 293 cells

  • Accession

    Q9CR75

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Mouse

    • Sequence

      MASAWPRSLPQILVLGFGLVLMRAAAGEQAPGTSPCSSGSSWSADLDKCM DCASCPARPHSDFCLGCAAAPPAHF

    • Predicted molecular weight

      34 kDa

    • Amino acids

      1 to 75

    • Specifications

    Our Abpromise guarantee covers the use of ab157284 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      Functional Studies

      SDS-PAGE

    • Form

      Lyophilized

    • Additional notes

      Binds Human and mouse TWEAK.
      Inhibits TWEAK-mediated killing of Kym-1 target cells.

       This product was previously labelled as TWEAKR

       

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at -20ºC.

      Constituent: 99% PBS

      This product is an active protein and may elicit a biological response in vivo, handle with caution.

    • Reconstitution
      Reconstitute with 50µl sterile water to a concentration of 1 mg/ml. Further dilutions should be made with medium containing 5% fetal calf serum. After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.

    General Info

    • Alternative names

      • CD 266
      • CD266
      • CD266 antigen
      • FGF inducible 14
      • FGF-inducible 14
      • Fibroblast growth factor inducible immediate early response protein 14
      • Fibroblast growth factor-inducible immediate-early response protein 14
      • FN 14
      • FN14
      • TNFRSF 12A
      • TNFRSF12A
      • TNR12_HUMAN
      • Tumor necrosis factor receptor superfamily member 12A
      • TWEAK R
      • Tweak receptor
      • Tweak-receptor
      • TweakR
      see all

    • Function

      Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.

    • Tissue specificity

      Highly expressed in heart, placenta and kidney. Intermediate expression in lung, skeletal muscle and pancreas.

    • Sequence similarities

      Contains 1 TNFR-Cys repeat.

    • Cellular localization

      Membrane.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab157284? Please let us know so that we can cite the reference in this datasheet.

ab157284 has not yet been referenced specifically in any publications.

Preparation and Storage

  • CD 266
  • CD266
  • CD266 antigen

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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