Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Mouse TWEAKR/FN14 protein (Fc Chimera) (ab185863)

Key features and details

  • Expression system: Mammalian
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Tags: proprietary tag C-Terminus
  • Suitable for: SDS-PAGE, HPLC

Description

  • Product name

    Recombinant Mouse TWEAKR/FN14 protein (Fc Chimera)
    See all TWEAKR/FN14 proteins and peptides

  • Purity

    > 95 % SDS-PAGE.
    The purity of ab185863 is greater than 95%, as determined by SEC-HPLC and reducing SDS-PAGE.

  • Endotoxin level

  • Expression system

    Mammalian

  • Accession

    Q9CR75

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Mouse

    • Sequence

      EQAPGTSPCSSGSSWSADLDKCMDCASCPARPHSDFCLGCAAAPPAHFRL LWVDDIEGRMDEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMIS RTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVS VLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPS REEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSF FLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK

    • Predicted molecular weight

      33 kDa including tags

    • Amino acids

      28 to 79

    • Tags

      proprietary tag C-Terminus

    • Additional sequence information

      The recombinant fragment is fused with an FC tag.

    • Specifications

    Our Abpromise guarantee covers the use of ab185863 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

      HPLC

    • Form

      Lyophilized

    • Additional notes

       This product was previously labelled as TWEAKR

       

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 7.40
      Constituent: 100% PBS

      Lyophilized from a 0.2 µM filtered solution.

    • Reconstitution
      Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS.

    General Info

    • Alternative names

      • CD 266
      • CD266
      • CD266 antigen
      • FGF inducible 14
      • FGF-inducible 14
      • Fibroblast growth factor inducible immediate early response protein 14
      • Fibroblast growth factor-inducible immediate-early response protein 14
      • FN 14
      • FN14
      • TNFRSF 12A
      • TNFRSF12A
      • TNR12_HUMAN
      • Tumor necrosis factor receptor superfamily member 12A
      • TWEAK R
      • Tweak receptor
      • Tweak-receptor
      • TweakR
      see all

    • Function

      Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.

    • Tissue specificity

      Highly expressed in heart, placenta and kidney. Intermediate expression in lung, skeletal muscle and pancreas.

    • Sequence similarities

      Contains 1 TNFR-Cys repeat.

    • Cellular localization

      Membrane.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab185863? Please let us know so that we can cite the reference in this datasheet.

ab185863 has not yet been referenced specifically in any publications.

Preparation and Storage

  • CD 266
  • CD266
  • CD266 antigen

Images

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