Antibodies, Proteins, Kits and Reagents for Life Science

Key features and details

Expression system: Mammalian
Purity: > 95% SDS-PAGE
Endotoxin level:
Tags: proprietary tag C-Terminus
Suitable for: SDS-PAGE, HPLC

Product name

Recombinant Mouse TWEAKR/FN14 protein (Fc Chimera)
See all TWEAKR/FN14 proteins and peptides
Purity

> 95 % SDS-PAGE.
The purity of ab185863 is greater than 95%, as determined by SEC-HPLC and reducing SDS-PAGE.
Endotoxin level
Expression system

Mammalian
Accession

Q9CR75
Protein length

Protein fragment
Animal free

No
Nature

Recombinant
- Species
  
  Mouse
- Sequence
  
  EQAPGTSPCSSGSSWSADLDKCMDCASCPARPHSDFCLGCAAAPPAHFRL LWVDDIEGRMDEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMIS RTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVS VLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPS REEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSF FLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
- Predicted molecular weight
  
  33 kDa including tags
- Amino acids
  
  28 to 79
- Tags
  
  proprietary tag C-Terminus
- Additional sequence information
  
  The recombinant fragment is fused with an FC tag.

Our Abpromise guarantee covers the use of ab185863 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Applications

SDS-PAGE

HPLC
Form

Lyophilized
Additional notes

This product was previously labelled as TWEAKR
Concentration information loading...

Stability and Storage

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

pH: 7.40
Constituent: 100% PBS

Lyophilized from a 0.2 µM filtered solution.
Reconstitution

Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS.

Alternative names
- CD 266
- CD266
- CD266 antigen
- FGF inducible 14
- FGF-inducible 14
- Fibroblast growth factor inducible immediate early response protein 14
- Fibroblast growth factor-inducible immediate-early response protein 14
- FN 14
- FN14
- TNFRSF 12A
- TNFRSF12A
- TNR12_HUMAN
- Tumor necrosis factor receptor superfamily member 12A
- TWEAK R
- Tweak receptor
- Tweak-receptor
- TweakR
see all
Function

Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.
Tissue specificity

Highly expressed in heart, placenta and kidney. Intermediate expression in lung, skeletal muscle and pancreas.
Sequence similarities

Contains 1 TNFR-Cys repeat.
Cellular localization

Membrane.
Target information above from: UniProt accession Q9NP84 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols