Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Mouse IL1 Receptor I/IL-1R-1 protein (Fc Chimera) (ab215598)

Key features and details

  • Expression system: Mammalian
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Suitable for: SDS-PAGE

Description

  • Product name

    Recombinant Mouse IL1 Receptor I/IL-1R-1 protein (Fc Chimera)
    See all IL1 Receptor I/IL-1R-1 proteins and peptides

  • Purity

    > 95 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    Mammalian

  • Accession

    P13504

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Mouse

    • Sequence

      LEIDVCTEYPNQIVLFLSVNEIDIRKCPLTPNKMHGDTIIWYKNDSKTPI SADRDSRIHQQNEHLWFVPAKVEDSGYYYCIVRNSTYCLKTKVTVTVLEN DPGLCYSTQATFPQRLHIAGDGSLVCPYVSYFKDENNELPEVQWYKNCKP LLLDNVSFFGVKDKLLVRNVAEEHRGDYICRMSYTFRGKQYPVTRVIQFI TIDENKRDRPVILSPRNETIEADPGSMIQLICNVTGQFSDLVYWKWNGSE IEWNDPFLAEDYQFVEHPSTKRKYTLITTLNISEVKSQFYRYPFICVVKN TNIFESAHVQLIYPVPDFKIEGRDMDPKSCDKTHTCPPCPAPELLGGPSV FLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTK PREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAK GQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENN YKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKS LSLSPGK

    • Predicted molecular weight

      64 kDa including tags

    • Amino acids

      20 to 338

    • Additional sequence information

      Fc tag at the C-terminus.

    • Specifications

    Our Abpromise guarantee covers the use of ab215598 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Lyophilized

    • Additional notes

      Previously labelled as IL1 Receptor I. 

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at -20°C. Avoid freeze / thaw cycle.

      pH: 7.40
      Constituent: 100% PBS

      Lyophilized from a 0.2 µm filtered solution.

    • Reconstitution
      Dissolve the lyophilized protein in ddH2O. It is not recommended to reconstitute to a concentration less than 100 µg/ml.

    General Info

    • Alternative names

      • Antigen CD121a
      • CD121 antigen-like family member A
      • CD121a
      • CD121a antigen
      • D2S1473
      • IL 1
      • IL 1R 1
      • IL 1R alpha
      • IL 1RT1
      • IL-1R-1
      • IL-1R-alpha
      • IL-1RT-1
      • IL-1RT1
      • IL1 inhibitor
      • IL1 Receptor I
      • IL1R
      • IL1R1
      • IL1R1_HUMAN
      • IL1RA
      • IL1RN
      • IL1RT1
      • Interleukin 1 receptor alpha type 1
      • Interleukin 1 receptor antagonist protein (IRAP)
      • Interleukin 1 receptor type I
      • Interleukin receptor 1
      • Interleukin-1 receptor alpha
      • Interleukin-1 receptor type 1
      • Interleukin-1 receptor type I
      • p80
      see all

    • Function

      Receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappa-B. Signaling involves formation of a ternary complex containing IL1RAP, TOLLIP, MYD88, and IRAK1 or IRAK2.

    • Sequence similarities

      Belongs to the interleukin-1 receptor family.
      Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
      Contains 1 TIR domain.

    • Cellular localization

      Membrane.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab215598? Please let us know so that we can cite the reference in this datasheet.

ab215598 has not yet been referenced specifically in any publications.

Preparation and Storage

  • Antigen CD121a
  • CD121 antigen-like family member A
  • CD121a

Images

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