Antibodies, Proteins, Kits and Reagents for Life Science

Key features and details

Expression system: Mammalian
Purity: > 95% SDS-PAGE
Endotoxin level:
Suitable for: SDS-PAGE

Product name

Recombinant Mouse IL1 Receptor I/IL-1R-1 protein (Fc Chimera)
See all IL1 Receptor I/IL-1R-1 proteins and peptides
Purity

> 95 % SDS-PAGE.
Endotoxin level
Expression system

Mammalian
Accession

P13504
Protein length

Protein fragment
Animal free

No
Nature

Recombinant
- Species
  
  Mouse
- Sequence
  
  LEIDVCTEYPNQIVLFLSVNEIDIRKCPLTPNKMHGDTIIWYKNDSKTPI SADRDSRIHQQNEHLWFVPAKVEDSGYYYCIVRNSTYCLKTKVTVTVLEN DPGLCYSTQATFPQRLHIAGDGSLVCPYVSYFKDENNELPEVQWYKNCKP LLLDNVSFFGVKDKLLVRNVAEEHRGDYICRMSYTFRGKQYPVTRVIQFI TIDENKRDRPVILSPRNETIEADPGSMIQLICNVTGQFSDLVYWKWNGSE IEWNDPFLAEDYQFVEHPSTKRKYTLITTLNISEVKSQFYRYPFICVVKN TNIFESAHVQLIYPVPDFKIEGRDMDPKSCDKTHTCPPCPAPELLGGPSV FLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTK PREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAK GQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENN YKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKS LSLSPGK
- Predicted molecular weight
  
  64 kDa including tags
- Amino acids
  
  20 to 338
- Additional sequence information
  
  Fc tag at the C-terminus.

Our Abpromise guarantee covers the use of ab215598 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Applications

SDS-PAGE
Form

Lyophilized
Additional notes

Previously labelled as IL1 Receptor I.
Concentration information loading...

Stability and Storage

Shipped at 4°C. Store at -20°C. Avoid freeze / thaw cycle.

pH: 7.40
Constituent: 100% PBS

Lyophilized from a 0.2 µm filtered solution.
Reconstitution

Dissolve the lyophilized protein in ddH2O. It is not recommended to reconstitute to a concentration less than 100 µg/ml.

Alternative names
- Antigen CD121a
- CD121 antigen-like family member A
- CD121a
- CD121a antigen
- D2S1473
- IL 1
- IL 1R 1
- IL 1R alpha
- IL 1RT1
- IL-1R-1
- IL-1R-alpha
- IL-1RT-1
- IL-1RT1
- IL1 inhibitor
- IL1 Receptor I
- IL1R
- IL1R1
- IL1R1_HUMAN
- IL1RA
- IL1RN
- IL1RT1
- Interleukin 1 receptor alpha type 1
- Interleukin 1 receptor antagonist protein (IRAP)
- Interleukin 1 receptor type I
- Interleukin receptor 1
- Interleukin-1 receptor alpha
- Interleukin-1 receptor type 1
- Interleukin-1 receptor type I
- p80
see all
Function

Receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappa-B. Signaling involves formation of a ternary complex containing IL1RAP, TOLLIP, MYD88, and IRAK1 or IRAK2.
Sequence similarities

Belongs to the interleukin-1 receptor family.
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 TIR domain.
Cellular localization

Membrane.
Target information above from: UniProt accession P14778 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols