Antibodies, Proteins, Kits and Reagents for Life Science

Recombinant Human TNFSF18/GITRL protein (Fc Chimera) (ab182828)

Key features and details

Expression system: HEK 293 cells
Purity: > 95% SDS-PAGE
Endotoxin level:
Suitable for: SDS-PAGE

Alternative names
- Activation inducible TNF related ligand
- Activation-inducible TNF-related ligand
- AITR ligand
- AITRL
- GITR ligand
- GITRL
- Glucocorticoid induced TNF related ligand
- Glucocorticoid induced TNFR related protein ligand
- Glucocorticoid-induced TNF-related ligand
- hGITRL
- MGC138237
- TL6
- TNF18_HUMAN
- TNFSF18
- TNLG2A
- Tumor necrosis factor (ligand) superfamily member 18
- Tumor necrosis factor ligand 2A
- Tumor necrosis factor ligand superfamily member 18
see all
Function

Cytokine that binds to TNFRSF18/AITR/GITR. Important for interactions between activated T-lymphocytes and endothelial cells and may modulate T-lymphocyte survival in peripheral tissues.
Tissue specificity

Expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells.
Sequence similarities

Belongs to the tumor necrosis factor family.
Cellular localization

Membrane.
Target information above from: UniProt accession Q9UNG2 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

SDS-PAGE - Recombinant Human TNFSF18/GITRL protein (Fc Chimera) (ab182828)

The purity of ab182828 was determined by DTT-reduced (+) and non-reduced (-) SDS-PAGE and staining overnight with Coomassie Blue.

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