Recombinant mouse TNFSF18/GITRL protein (Fc Chimera Active) (ab219721)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 95% SDS-PAGE
- Endotoxin level:
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE
Preparation and Storage
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Alternative names
- Activation inducible TNF related ligand
- Activation-inducible TNF-related ligand
- AITR ligand
see all -
Function
Cytokine that binds to TNFRSF18/AITR/GITR. Important for interactions between activated T-lymphocytes and endothelial cells and may modulate T-lymphocyte survival in peripheral tissues. -
Tissue specificity
Expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. -
Sequence similarities
Belongs to the tumor necrosis factor family. -
Cellular localization
Membrane. - Information by UniProt
Images
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Functional Studies - Recombinant mouse TNFSF18/GITRL protein (Fc Chimera Active) (ab219721)Immobilized Mouse GITR (His Tag) at 5 µg/mL (100 µL/well) can bind Mouse GITR Ligand (Fc Tag) with a linear range of 5-156 ng/mL (QC tested).
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SDS-PAGE - Recombinant mouse TNFSF18/GITRL protein (Fc Chimera Active) (ab219721)SDS-PAGE analysis of ab219721 under reducing (lane 1) and non-reducing conditions (lane 2); stained overnight with Coomassie Blue.
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Functional Studies - Recombinant mouse TNFSF18/GITRL protein (Fc Chimera Active) (ab219721)Immobilized Mouse GITR, His Tag at 10 μg/mL (100 μL/well) can bind ab219721 with a linear range of 0.007-0.256 μg/mL.
