Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human TNFSF18/GITRL protein (Tagged-His Tag) (ab196127)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Tags: His tag C-Terminus
  • Suitable for: HPLC, SDS-PAGE

Description

  • Product name

    Recombinant Human TNFSF18/GITRL protein (Tagged-His Tag)
    See all TNFSF18/GITRL proteins and peptides

  • Purity

    > 95 % SDS-PAGE.
    Purity of ab196127 is greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.

  • Endotoxin level

  • Expression system

    HEK 293 cells

  • Accession

    Q9UNG2

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      ETAKEPCMAKFGPLPSKWQMASSEPPCVNKVSDWKLEILQNGLYLIYGQV APNANYNDVAPFEVRLYKNKDMIQTLTNKSKIQNVGGTYELHVGDTIDLI FNSEHQVLKNNTYWGIILLANPQFISVDHHHHHH

    • Predicted molecular weight

      15 kDa including tags

    • Amino acids

      74 to 199

    • Tags

      His tag C-Terminus

    • Specifications

    Our Abpromise guarantee covers the use of ab196127 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      HPLC

      SDS-PAGE

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

      pH: 7.4
      Constituent: 100% PBS

      Lyophilized from a 0.2 µm filtered solution

    General Info

    • Alternative names

      • Activation inducible TNF related ligand
      • Activation-inducible TNF-related ligand
      • AITR ligand
      • AITRL
      • GITR ligand
      • GITRL
      • Glucocorticoid induced TNF related ligand
      • Glucocorticoid induced TNFR related protein ligand
      • Glucocorticoid-induced TNF-related ligand
      • hGITRL
      • MGC138237
      • TL6
      • TNF18_HUMAN
      • TNFSF18
      • TNLG2A
      • Tumor necrosis factor (ligand) superfamily member 18
      • Tumor necrosis factor ligand 2A
      • Tumor necrosis factor ligand superfamily member 18
      see all

    • Function

      Cytokine that binds to TNFRSF18/AITR/GITR. Important for interactions between activated T-lymphocytes and endothelial cells and may modulate T-lymphocyte survival in peripheral tissues.

    • Tissue specificity

      Expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells.

    • Sequence similarities

      Belongs to the tumor necrosis factor family.

    • Cellular localization

      Membrane.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab196127? Please let us know so that we can cite the reference in this datasheet.

ab196127 has not yet been referenced specifically in any publications.

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

    pH: 7.4
    Constituent: 100% PBS

    Lyophilized from a 0.2 µm filtered solution

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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