Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human TLT-1 protein (Fc Chimera) (ab185864)

Key features and details

  • Expression system: Mammalian
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Tags: proprietary tag C-Terminus
  • Suitable for: SDS-PAGE, HPLC

Description

  • Product name

    Recombinant Human TLT-1 protein (Fc Chimera)
    See all TLT-1 proteins and peptides

  • Purity

    > 95 % SDS-PAGE.
    The purity of ab185864 is greater than 95%, as determined by SEC-HPLC and reducing SDS-PAGE.

  • Endotoxin level

  • Expression system

    Mammalian

  • Accession

    Q86YW5

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      QGIVGSLPEVLQAPVGSSILVQCHYRLQDVKAQKVWCRFLPEGCQPLVSS AVDRRAPAGRRTFLTDLGGGLLQVEMVTLQEEDAGEYGCMVDGARGPQIL HRVSLNILPPEEEEETHKIGSLAENAFSDPAGSANPLEPSQDEKSIPVDD IEGRMDEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEV TCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVL HQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMT KNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSK LTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK

    • Predicted molecular weight

      43 kDa including tags

    • Amino acids

      16 to 162

    • Tags

      proprietary tag C-Terminus

    • Additional sequence information

      The recombinant fragment was fused with an FC tag.

    • Specifications

    Our Abpromise guarantee covers the use of ab185864 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

      HPLC

    • Form

      Lyophilized

    • Additional notes

      Previously labelled as TREML1. 

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 7.40
      Constituent: 100% PBS

      Lyophilized from an 0.2 µM filtered solution.

    • Reconstitution
      Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 µg/ml.Dissolve the lyophilized protein in 3X PBS.

    General Info

    • Alternative names

      • dJ238O23.3
      • GLTL1825
      • MGC119173
      • PRO3438
      • TLT 1
      • TLT-1
      • TLT1
      • TREM like transcript 1
      • Trem like transcript 1 protein
      • Trem-like transcript 1 protein
      • TREML 1
      • Treml1
      • Triggering receptor expressed on myeloid cells like 1
      • Triggering receptor expressed on myeloid cells like protein 1
      • Triggering receptor expressed on myeloid cells-like protein 1
      • TRML1_HUMAN
      see all

    • Function

      Cell surface receptor that may play a role in the innate and adaptive immune response.

    • Tissue specificity

      Detected in platelets, monocytic leukemia and in T-cell leukemia.

    • Sequence similarities

      Contains 1 Ig-like V-type (immunoglobulin-like) domain.

    • Post-translational
      modifications

      Phosphorylated on tyrosine residues.

    • Cellular localization

      Cell membrane. Cytoplasm. Sequestered in cytoplasmic vesicles in resting platelets. Transported to the cell surface after stimulation by thrombin. Soluble fragments can be released into the serum by proteolysis.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab185864? Please let us know so that we can cite the reference in this datasheet.

ab185864 has not yet been referenced specifically in any publications.

Preparation and Storage

  • dJ238O23.3
  • GLTL1825
  • MGC119173

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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