Recombinant Human Sex Hormone Binding Globulin/SHBG protein (ab159505)
Key features and details
- Expression system: Wheat germ
- Tags: GST tag N-Terminus
- Suitable for: ELISA, WB
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Product name
Recombinant Human Sex Hormone Binding Globulin/SHBG protein
See all SHBG proteins and peptides -
Expression system
Wheat germ -
Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
DPPAVHLSNGPGQEPIAVMTFDLTKITKTSSSFEVRTWDPEGVIFYGDTN PKDDWFMLGLRDGRPEIQLHNHWAQLTVGAGPRLDDGRWHQVEVKMEGDS -
Amino acids
41 to 140 -
Tags
GST tag N-Terminus
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Preparation and Storage
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Alternative names
- ABP
- Androgen binding protein
- SBP
see all -
Function
Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. -
Tissue specificity
Isoform 1 and isoform 2 are present in liver and testis. -
Sequence similarities
Contains 2 laminin G-like domains. -
Cellular localization
Secreted. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis. - Information by UniProt
Images
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SDS-PAGE - Recombinant Human Sex Hormone Binding Globulin/SHBG protein (ab159505)ab159505 on a 12.5% SDS-PAGE stained with Coomassie Blue.