Native Human SHBG protein (ab151275)
Key features and details
- Expression system: Native
- Suitable for: IA, ELISA
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Product name
Native Human SHBG protein
See all SHBG proteins and peptides -
Expression system
Native -
Protein length
Full length protein -
Animal free
No -
Nature
Native -
-
Species
Human -
Predicted molecular weight
45 kDa
-
Preparation and Storage
-
Alternative names
- ABP
- Androgen binding protein
- SBP
see all -
Function
Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. -
Tissue specificity
Isoform 1 and isoform 2 are present in liver and testis. -
Sequence similarities
Contains 2 laminin G-like domains. -
Cellular localization
Secreted. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis. - Information by UniProt
