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Signal Transduction Growth Factors/Hormones TGF

Recombinant human BMP2 protein (Animal Free) (ab217405)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 98% SDS-PAGE
  • Active: Yes
  • Suitable for: Functional Studies, SDS-PAGE, HPLC

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Description

  • Product name

    Recombinant human BMP2 protein (Animal Free)
    See all BMP2 proteins and peptides
  • Biological activity

    Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells.  The expected ED50 for this effect is 0.5-1.0 μg/ml.

  • Purity

    > 98 % SDS-PAGE.
    >98% by HPLC.
  • Expression system

    Escherichia coli
  • Accession

    P12643
  • Protein length

    Full length protein
  • Animal free

    Yes
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR
    • Predicted molecular weight

      26 kDa
    • Amino acids

      283 to 396
    • Additional sequence information

      This product is for the mature full length protein. The signal peptide and propeptide are not included.

Preparation and Storage

  • Alternative names

    • BDA2
    • BMP-2
    • BMP-2A
    • Bmp2
    • BMP2_HUMAN
    • BMP2A
    • Bone morphogenetic protein 2
    • Bone morphogenetic protein 2A
    see all
  • Function

    Induces cartilage and bone formation.
  • Tissue specificity

    Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.
  • Sequence similarities

    Belongs to the TGF-beta family.
  • Cellular localization

    Secreted.
  • Target information above from: UniProt accession P12643 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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