Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant human BMP2 protein (ab200278)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Active: Yes
  • Suitable for: SDS-PAGE, HPLC, Functional Studies

Description

  • Product name

    Recombinant human BMP2 protein
    See all BMP2 proteins and peptides

  • Biological activity

    The ED50 as determined by the cytolysis of MC3T3-E1 cells is less than 50 ng/mL.

  • Purity

    > 95 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    Escherichia coli

  • Accession

    P12643

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MQAKHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPF PLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVV LKNYQDMVVE GCGCR

    • Predicted molecular weight

      26 kDa

    • Amino acids

      283 to 396

    • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab200278 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        SDS-PAGE

        HPLC

        Functional Studies

      • Form

        Lyophilized
      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

        pH: 3.50
        Constituent: 0.29% Sodium citrate

        This product is an active protein and may elicit a biological response in vivo, handle with caution.

      • Reconstitution
        We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in 10mM HAc to a concentration of 0.1-1.0 mg/mL.

      General Info

      • Alternative names

        • BDA2
        • BMP-2
        • BMP-2A
        • Bmp2
        • BMP2_HUMAN
        • BMP2A
        • Bone morphogenetic protein 2
        • Bone morphogenetic protein 2A
        see all

      • Function

        Induces cartilage and bone formation.

      • Tissue specificity

        Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.

      • Sequence similarities

        Belongs to the TGF-beta family.

      • Cellular localization

        Secreted.
      • Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab200278? Please let us know so that we can cite the reference in this datasheet.

    ab200278 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • BDA2
      • BMP-2
      • BMP-2A
      • Bmp2
      • BMP2_HUMAN
      • BMP2A
      • Bone morphogenetic protein 2
      • Bone morphogenetic protein 2A
      see all

    • Function

      Induces cartilage and bone formation.

    • Tissue specificity

      Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.

    • Sequence similarities

      Belongs to the TGF-beta family.

    • Cellular localization

      Secreted.
    • Information by UniProt

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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